MagSi-protein A and MagSi-protein G beads
can be used to detect or isolate target biomarkers like relevant proteins or peptides by coupling the Fc domain of the IgG antibody for a target biomarker. The advantage of protein G an A beads, compared to streptavidin beads, is that the antibody does not need to be biotinylated and the binding is reversible. No cross linking of the antibody is needed using our protocols and the target biomarker can be eluted under native conditions for downstream analysis!
MagSi-proteomics reversed phase beads
are magnetic beads that are an ideal tool for the purification, concentration and desalting of peptides and protein digests. The surface of the beads has been modified with C4, C8 and C18 alkyl groups that are typical for reversed phase applications. MagSi proteomics RP beads are an ideal tool for automated, parallel sample preparation prior to mass spectrometry and provide best quality mass spectrometry data. A typical protein tryptic digest of up to 1 nmol in total can now be desalted at prices below 1 EUR without time consuming column filling or pipetting.
are building block beads that are suitable to detect and capture your own specific biomarker, whether it is a protein or other biomolecule to the surface of the beads. Low unspecific binding, easy to use protocols and unique advantages of the MagSi-S-Tools make these beads an ideal tool for your life science research project.
Our dedicated team of chemists, biologists and biomarker experts can be your sparring partner in selecting the right bead for your intended application, or can help to customize bead-chemistry to your demand and the biomarker’s specifications. Click here to see many but not all possibilities Magnamedics provides to develop your specific bead for your specific biomarker application.
Download our Biomarker brochure